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Buzzards Bay, Eel Pond, Great Harbor are in a deep-freeze. Our hardworking MBL grounds crews have been plowing, shoveling, sanding, and carving narrow walkways throughout campus since January. Shoes, cars,and stairwells are filthy, parking lots are flanked by ugly snow mountains, and patience with snow shovels, overcoats, scarves, gloves, boots, ear warmers, etc., is quickly waning. Even the Eel Pond ducks seem to be crying “UNCLE!” And more snow is predicted for this week.

So how are we surviving the tough winter weather?

Woods Hole’s natural, transient beauty (less the parking lots) keeps us charmed and impressed. Gorgeous sunsets, glimmering snowscapes, ice-capped shorelines, and oddly translucent waters make Woods Hole appear extraordinarily shiny and picturesque. It’s cold and inconvenient, but we all agree the village looks pretty darned good in snow.

Along with breathtaking winter views, good old New England fun energizes and entertains us, despite the bitter cold temperatures. Just today, at lunchtime, a hearty handful of ice skaters ventured out onto a solidly frozen Eel Pond. (The last time the pond froze was more than a decade ago, so this was quite a novelty for most.) Colleagues bundled up and headed out to the dock to watch the skaters, or to embark on their own personal historic walk across the water they are used to boating on. (Yes, that is MBL’s Gemma Captain Bill Klimm donning skates and joining in a round of pick-up hockey. No collecting boat trips today!)

Yes, Woods Hole is exceptionally beautiful and interesting under winter’s weight. But, really, spring is welcome anytime now….

— by Beth Liles

Photos by Hunt Willard, Pam Wilmot, and Beth Liles.

 

 

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The MBL-UChicago-Argonne Exploratory Research Fund provides seed funding for UChicago/Argonne collaborations with MBL resident and Whitman scientists. Congratulations to the first recipients of these awards, who are listed below. The University is accepting a second round of proposals until February 20. Please see a feature article about the program here.


First Recipients of MBL-UChicago-Argonne Exploratory Research Fund Awards

  • Jocelyn Malamy and Joel Smith: “Clytia hemisphaerica, a New Marine Model for Regeneration”
  • Patrick La Rivière, Hari Shroff, and Daniel Colón-Ramos: “Improving diSPIM Microscopy Through Advanced Computational Methods”
  • Stephanie E. Palmer and Roger T. Hanlon: “Quantifying Cuttlefish Camouflage”
  • Gordon Kindlmann, Rudolf Oldenbourg, and Nicola Ferrier: “Light Field Imaging of Anisotropic Materials”
Bill Klimm, captain of the Gemma, the MBL's collecting vessel. Credit: Daniel Cojanu

Bill Klimm, captain of the Gemma, the MBL’s collecting vessel. Credit: Daniel Cojanu

When Nature began pursuing a story on “unsung heroes” in science — the behind-the-scenes staff who make the whole operation happen — it became clear that plenty of people at the MBL fit that bill. One is Bill Klimm, captain of the Gemma, who as a longtime fisherman knows not only how to operate the boat, but where to find the elusive fish and other marine organisms used for MBL research. Nature published a wonderful profile of Klimm this week, including the video below. Thanks to Bill, Dave Remsen, Dan Sullivan, and everyone who works hard every day to make the MBL’s collecting operation succeed!

 

MBL Adjunct Scientist Amy Gladfelter can now add “video producer” to her resume. Tapped to make her science “visible to the world” by Celldance Studios, a project of the American Society for Cell Biology (ASCB), Gladfelter came up with an aesthetically beautiful, simply told video about her discoveries of what goes wrong when cells form toxic aggregates, such as in Alzheimer’s disease. Her mini-movie, called “Companions in Discovery,” was filmed partly at MBL and partly at Dartmouth College, where she is an Associate Professor of Biological Sciences. It premiered for an appreciative audience in December at the ASCB annual meeting in Philadelphia.

“I like the end of the film, where members of [Gladfelter’s] lab talk briefly on camera. These young faces are the future of cell biology,” said Simon Atkinson, chairman of the ASCB’s Public Information Committee, which sponsors Celldance Studios.

Celldance Studios gave Gladfelter $1,000 to underwrite her costs, and provided video editing and post-production support. The original score is by Hollywood film composer Ted Masur, son of cell biologist Sandra Masur. More information is here.

 

Huntington Willard, an innovative leader in the fields of genetics and genome biology who has built comprehensive research centers at leading institutions, has been appointed the next president and director of the Marine Biological Laboratory in Woods Hole, Massachusetts.

University of Chicago President Robert J. Zimmer, who is also Chairman of the MBL’s Board of Trustees, announced the appointment to the MBL and University communities. MBL is an affiliate of the University of Chicago, a relationship designed to yield novel avenues for scientific discovery and education at both institutions.

At the MBL, Willard will lead one of the world’s foremost centers for biological research, international collaboration and education. Willard, currently the Arts & Sciences Professor of Biology and Genome Sciences at Duke University, will begin his appointment at the MBL on January 1, 2015.

Huntington Willard

Huntington Willard

Willard has earned a reputation as a groundbreaking scientist, a strong leader and builder of complex academic initiatives, as well as a talented educator who has received multiple teaching awards. From 2003 to 2014 he was the founding Director of the Duke Institute for Genome Sciences and Policy, a highly interdisciplinary unit that spanned the life sciences, engineering, medicine, social sciences and the humanities. For that program, Willard recruited 35 faculty members to Duke across 21 departments and established broad institutional strength in the genome sciences. He had previously chaired the Department of Genetics at Case Western Reserve University, where he also built a widely respected program of research and education.

As a researcher, Willard has explored many facets of genetics and genome biology, with a particular interest in the structure and function of chromosomes, the epigenetic regulation of gene silencing, and the evolution and organization of complex genomes. He is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences and has won many awards for genetics scholarship, including the William Allan Award from the American Society of Human Genetics.

“Hunt Willard is an outstanding scholar and a proven scientific leader who has created programs that have earned international respect,” said Zimmer. “He exemplifies the values that guide the Marine Biological Laboratory and the University of Chicago — wide-ranging collaboration, eagerness to explore and define new fields of study, and a dedication to discovery through engaged education. We are delighted to welcome him to this community, and confident that he will lead the MBL in a way that preserves its strengths, creates new opportunities for growth, and takes advantage of the relationship with the University of Chicago.”

Willard said he was attracted by the MBL’s historic role as a beacon for scientists from around the world, including its renowned summer courses and creative year-round programs of research and education.

“I’m honored to be named the next president and director of MBL,” Willard said. “The MBL has enjoyed such a strong tradition of integrating research and education since its founding, and offers wonderful opportunities to develop and implement novel strategies for tackling some of the most pressing questions in life sciences and biomedical research today. The highly interdisciplinary nature of its year-round and visiting scientists and students offers unique combinations of scholarship, teamwork and adaptability that can’t be easily matched elsewhere. I can’t imagine a place that better illustrates the values of integrated research and education that are important to me — as a scientist, an educator and as a leader. I look forward with great enthusiasm to joining this community, at both MBL and the University of Chicago.”

Jennifer Morgan, an MBL scientist and associate director of the Eugene Bell Center for Regenerative Biology and Tissue Engineering, said Willard is a perfect fit for the MBL’s intellectual culture.

“As a leader who has brought together researchers with many diverse kinds of expertise, Hunt Willard is an exceptional choice to enrich the spirit of innovation and collaboration that has guided the MBL since its founding in 1888,” Morgan said.

The MBL is known as an institution dedicated to scientific discovery and improving the human condition through research and education in biology, biomedicine and environmental science. In July 2013 the MBL and the University of Chicago formed an affiliation that is producing growing collaborations between the two institutions and researchers at Argonne National Laboratory, which is managed by UChicago and has many research ties to the University.

In addition to his leadership of the MBL, Willard will have a faculty appointment in the Department of Human Genetics at the University of Chicago. Prior to his appointments at Duke and Case Western Reserve, Willard held faculty positions at the University of Toronto and Stanford University and was founding president and director of the University Hospitals of Cleveland Research Institute. He received his PhD in genetics from Yale University and his AB degree in biology from Harvard University.

Willard is widely considered a leading figure among American geneticists, having authored or contributed to more than 300 scholarly publications, providing fundamental insights and new tools for studying how cells inactivate genes on the X chromosome and what DNA sequences are involved in chromosome segregation during cell division. His team also received international attention in 1997 when it constructed the world’s first human artificial chromosome.

“What’s so extraordinary about Hunt Willard’s academic career is his demonstrated ability to lead the charge in scientific discovery, both as an investigator and as a director of several large, ambitious programs,” said Neil Shubin, the Robert R. Bensley Distinguished Service Professor of Organismal Biology and Anatomy and associate dean for academic strategy in UChicago’s Biological Sciences Division. “He has a sense of where fields are going, and an ability to identify and recruit the best academic talent. That’s going to make him an outstanding leader for the MBL, and a great colleague for all of us.”

Sally Kornbluth, provost of Duke University and the James B. Duke Professor of Pharmacology and Cancer Biology, praised Willard’s contributions at Duke.

“Hunt Willard is a stellar scientist, an energetic teacher and an innovative leader who helped make genomics a point of excellence at Duke,” Kornbluth said. “His appointment at the MBL heralds an exciting opportunity for the laboratory.”

Willard will succeed Arthur M. Sussman, the MBL’s interim president and director, who assumed that role in November with the departure of former president and director Joan Ruderman. President Zimmer sent a message to the MBL community last May praising Ruderman’s record of commitment to the lab, which began in 1974 when she first arrived as a post-doctoral researcher.

Collaborative marine science took a leap of global proportions on June 21, 2014. At carefully orchestrated times on that day, hundreds of scientists around the world collected ocean samples, using standardized protocols, as part of the first international Ocean Sampling Day (OSD). They were united by the goal of identifying the microbial communities in all the samples–no small task given that one drop of seawater contains about 20 million microbes.

This movie features MBL Associate Scientist Linda Amaral-Zettler, who took a lead role in OSD as a scientific adviser to the project’s European sponsor, MicroB3, and who actively sampled and helped coordinate sampling in the Azorean Islands. Building a knowledge base of marine microbes is critical for understanding the impact of global challenges to ocean health, such as a warming climate.

“Sampling is expensive,” Amaral-Zettler says. “The more we can leverage individual regional efforts and resources, the better we will be in protecting the ocean.”

As soon as they were collected, the samples were frozen and shipped to Max Planck Institute for Marine Microbiology in Bremen, Germany. The next step is to identify “who” are in the samples through DNA extraction and analysis.

OSD will take place again in 2015 and hopefully into the future, Amaral Zettler says, which would provide a long-term perspective on how marine microbial diversity changes over time. “We need to understand how things are changing in order to protect them.”

Akash Srivastava, a student in the Brown-MBL Graduate Program in Biological and Environmental Sciences, successfully defended his Ph.D. dissertation entitled “Transdifferentiation of Liver to Pancreas” on August 18 at Brown University. Srivastava, a student in the Molecular Biology, Cell Biology and Biochemistry Department (MCB) at Brown, conducted his research at the MBL’s Eugene Bell Center for Regenerative Biology and Tissue Engineering under the advisement of MBL Associate Scientist Marko Horb. His doctoral committee members also included Rich Freiman, Kristi Wharton, and Eric Morrow from the MCB Department.

Srivastava’s doctoral research helped to elucidate the molecular mechanisms involved in transdifferentiation of liver to pancreas in the frog Xenopus laevis. He identified a previously unknown role of a highly conserved beta-catenin inhibitor protein (Chibby) in transdifferentiation of liver to pancreas and in normal pancreas development. His research also provided a better understanding of the function of Wnt/beta catenin signaling in pancreas development. Funding for his research came from the Horb lab at with grant support from the National Institutes of Health.

After completing his final manuscripts, Srivastava plans to work as a validation consultant in the pharmaceutical industry.

Akash Srivastava defends his thesis at Brown University for his Ph.D. in the Brown-MBL Graduate Program.

Akash Srivastava defends his thesis at Brown University for his Ph.D. in the Brown-MBL Graduate Program.

Keating-at-OBFS-NML-meeting-9-2014-cropU.S. Representative Bill Keating visited Lillie Auditorium this morning to address members of the Organization of Biological Field Stations (OBFS) and the National Association of Marine Laboratories (NAML), who are holding a joint meeting at the MBL.

Keating remarked on the exponential advances in information technology that allow scientists to transmit data from field stations “instantly, accurately, and efficiently.” He also commended the two groups for collaborating. “Working jointly, with the information you gather, creates enormous opportunities” in the private sector as well as in environmental science, Keating said.

Keating represents the 9th district of Massachusetts, which includes Cape Cod and the islands. He was invited to the MBL by Sarah Oktay, president of OBFS and director of the UMass Boston Nantucket Field Station. MBL Senior Scientist Alan Kuzirian is the founding secretary/treasurer of NAML ( from 1990-2014).

Jerry Melillo, distinguished scientist at the MBL's Ecosystems Center, leads a panel discussion of the National Climate Assessment yesterday at the White House. Melillo is chairman of the advisory committee that prepared the assessment for interagency U.S. Global Change Research Program. Screen shot by Gina Hebert.

Jerry Melillo, Distinguished Scientist at the MBL’s Ecosystems Center, leads a panel discussion of the National Climate Assessment yesterday at the White House. Melillo is chairman of the National Climate Assessment and Development Advisory Committee. Screen shot by Gina Hebert.

The major messages of the Third National Climate Assessment released yesterday — climate change is already here, its impacts are being felt in every U.S. region, it is caused by human activity, and it is not too late to take action — were discussed far and wide, in thousands of news articles and broadcasts across the nation. For scientists like the MBL’s Jerry Melillo who have spent decades documenting global climate change, this is a great leap forward. This White House infographic summarizes some of the major findings of the Assessment, and outlines national plans to prepare for climate change impacts, reduce carbon pollution, and lead international efforts to address global climate change. Melillo is chairman of the federal advisory committee that prepared the assessment for the interagency U.S. Global Change Research Program.

 

A whimsical, enlightening video about cuttlefish camouflage by Jacob Gindi, a senior and biology major at Brown University, appeared in The New York Times last week. Gindi had encountered live cuttlefish when he visited the MBL’s Marine Resources Center as a student in The Art and Science of Visual Perception, a Brown course co-taught by Roger Hanlon of the MBL and Mark Milloff of Rhode Island School of Design. Gindi then had a chance to make a CreatureCast video in Casey Dunn’s Invertebrate Zoology class at Brown. Inspired by Hanlon’s research, Gindi’s artful video about the cuttlefish’s amazingly adaptive skin can be enjoyed by marine biology-lovers of all ages.

“It is so gratifying to see science and art promoted at this national/international scale,” says Hanlon, an MBL senior scientist and professor in Brown’s Ecology and Evolutionary Biology Department through the Brown-MBL Partnership and Graduate Program.

CreatureCast, a collaborative blog produced by members of the Dunn Lab, is supported by a National Science Foundation grant.

 

 

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